hrp0094p1-4 | Adrenal A | ESPE2021

Depression among insured children and young adults in the United States with congenital adrenal hyperplasia

Harasymiw Lauren , Grosse Scott , Cullen Kathryn , Bitsko Rebecca , Perou Ruth , Sarafoglou Kyriakie ,

Background: Individuals with congenital adrenal hyperplasia (CAH), a form of adrenal insufficiency, are exposed to daily non-physiologic, non-circadian cortisol profiles due to both the disease and therapeutic limitations. Dysfunction in the hypothalamic-pituitary-adrenal axis is strongly associated with depressive disorders. However, little is known about the prevalence of depression among children and young adults with CAH. We investigated the prevalence of ...